Accelerated Solvent Extraction (ASE®)

Accelerated Solvent Extraction (ASE)

OverviewIn-Cell Cleanup Tired of spending days on sample preparation? Tired of spending countless hours on labor-intensive sample preparation steps?

Accelerated Solvent Extraction (ASE®) is a patented technique for the extraction of solid and semisolid sample matrices using common solvents at elevated temperatures and pressures. ASE systems are available in the entry-level ASE 150 system, and fully automated ASE 350.

Extractions that normally take hours can be done in minutes using ASE with pH hardened pathways using Dionium™ components. Compared to techniques such as Soxhlet and sonication, ASE generates results in a fraction of the time.

The many steps involved in sample preparation can now be automated with ASE flow-through technology. Filtration and clean-up of solid samples can be achieved as part of the solvent extraction process in a single step. ASE offers a lower cost per sample than other techniques, reducing solvent consumption by up to 90%.


  • Extractions for sample sizes 1-100 g in minutes
  • Dramatic solvent reduction
  • Wide range of applications
  • Handles acidic and alkaline matrices
  • Approved for use by the U.S. EPA and CLP Program

Dionex ASE systems can be applied to many industries



  • Pesticides and herbicides
  • PAHs and semi-volatiles
  • PCBs
  • Dioxins and furans
  • TPH (DRO)
  • Explosives
  • Air sampling cartridges (XAD and PUFs)
  • Brominated flame retardants
  • ASE meets all of the requirements for extraction under U.S. EPA SW-846 Method 6860 Method 3545A for Pressurized Fluid Extraction, and is accepted under CLP SOW OLMO4.2.

Pharmaceutical and Natural Products

  • Active ingredients
  • Drug delivery devices and packaging

Polymers Using ASTM Method D7210

  • Oils and organic acids
  • Xylene solubles
  • Polymer additives (polyolefins, PVC)


  • Vitamins and antibiotics
  • Contaminants
  • Natural products
  • Pesticides and herbicides in food
  • Pesticide residues
  • Fat and lipid determination after acid pre-treatment
  • Herbal and dietary supplements

Consumer Products

  • Detergents
  • Paper and pulp
  • Bio fuels
  • Textiles and fibers

Accelerated Solvent Extraction Systems


  • The ASE 150 system is an entry level system for laboratories with modest throughput.
  • The ASE 350 system is a sequential extraction system capable of automated extraction of up to 24 samples.

Accelerated Solvent Extraction Accessories

  • Dionex offers ASE accessories to improve productivity and allow sample tracking.

Accelerated Solvent Extraction Consumables

  • Dionex offers parts and accessories are designed and manufactured to meet the unique specifications of ASE® instrumentation and meet the quality requirements of modern analytical laboratories.

Accelerated Solvent Extraction (ASE) 150and 350 System