Solid-Phase Extraction (SPE)
Solid-phase extraction (SPE) is a technique for liquid-liquid
extraction that is used to remove certain compounds from a mixture
of impurities based on their physical and chemical properties.
Analytical laboratories use SPE to concentrate and purify samples
for analysis. SPE can be used to isolate analytes of interest from
a wide variety of matrices, including urine, blood, beverage, and
water samples. SPE requirements vary depending on the amount of
sample required. SPE systems can be separated into large or small
volume techniques. Large volume techniques generally use 100 mL or
more of liquid sample.
The Mechanics of SPE

The
AutoTrace® 280 instrument performs
automated solid-phase extractions (SPE) of large-volume liquid
samples for organic analysis. Liquid-liquid extractions that
normally take long hours can be automated using an AutoTrace SPE system
(Ссылка). Extraction steps that normally require constant attention
by chemists and technicians are performed automatically, and an
AutoTrace instrument significantly reduces sample handling compared
to techniques such as separatory funnel or vacuum manifold for SPE.
The tedious and time-consuming steps of liquid-liquid extraction
can be greatly decreased by automating the SPE steps of condition,
load, rinse, and elute. AutoTrace systems offer a lower sample
preparation cost-per-sample than other techniques by reducing
solvent and labor cost by up to 90%.
Benefits
Extractions for liquid sample sizes of 20 mL-20
L
- Dramatic solvent reduction and reduced sample handling
- Wide range of applications
- Automation
- Approved for use by many government agencies
See more about the AutoTrace® 280
instrument.